Ultrasound-promoted synthesis of (4 or 5)-aryl-2-aryloyl-(1H)-imidazoles in water
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چکیده
Article history: Received March 27, 2013 Received in Revised form August 27, 2013 Accepted 14 September 2013 Available online 14 September 2013 A green and efficient method for the synthesis of (4 or 5)-aryl-2-aryloyl-(1H)-imidazoles via self-condensation reaction of arylglyoxal hydrates in the presence of ammonium acetate using water as solvent under ultrasonic irradiation was reported. The reactions proceeded in high yields and very short reaction time. Introduced procedure is completely ecofriendly and don’t need any toxic organic solvent in all performing steps. In addition, we use computational chemistry for acquiring some information about the thermochemistry and geometrical structure of these imidazole derivatives. © 2013 Growing Science Ltd. All rights reserved.
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تاریخ انتشار 2013